Voriconazole for Injection) is indicated in the treatment of the following fungal infections:
Invasive aspergillosis in clinical trials, the majority of isolates recovered were Aspergillus fumigatus. There were a small number of cases of culture-proven disease due to species of Aspergillus other than A. Fumigatus.
Candidemia in nonneutropenic patients and the following Candida infections: disseminated infections in the skin and infections in the abdomen, kidney, bladder well, and wounds. Esophageal candidiasis.
Serious fungal infections caused by Scedosporium apiospermum (Asexual form of pseudallescheria boydii) and Fusarium spp. including Fusarium solani, in patients intolerant of or refractory to, other therapy.
Specimens for fungal culture and other relevant laboratory studies (including histopathology) should be obtained prior to therapy to isolate and identify causative organism(s). Therapy may be instituted before the results of the cultures and other laboratory studies are known. however, once these results become available, antifungal therapy should be adjusted accordingly.